By Guy F. Webster, Anthony V. Rawlings
Addressing some of the most ordinarily encountered stipulations obvious by means of the dermatologist, this resource analyzes the pathophysiology, review, analysis, scientific positive factors, and keep an eye on of pimples. With full-color illustrations, this resource delves into the to be had treatment plans for tough instances of pimples and scarring and gives specialist discussions of administration regimens together with topical and systemic cures, laser remedies, and new medicines.
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Additional resources for Acne and its therapy
19. Pie´rard GE. Follicle to follicle heterogeneity of sebum excretion. Dermatologica 1986; 173:61– 65. 20. Montagna W. Advances in Biology of the Skin. Vol. 4. : Pergamon Press, 1963. 21. Blume U, Ferracin J, Verschoore M, Czernielewski JM, Schaefer H. Physiology of the vellus hair follicle: hair growth and sebum excretion. Br J Dermatol 1991; 124: 21 – 28. 22. Pagnoni A, Kligman AM, el Gammal S, Stoudemayer T. Determination of density of follicles on various regions of the face by cyanoacrylate biopsy: correlation with sebum output.
5. Shuster S. Biological purpose of acne. Lancet 1976; 1:1328 –1329. 6. Zouboulis C. Sebaceous gland in human skin—the fantastic future of a skin appendage. J Invest Dermatol 2003; 120(6):xiv-xv. 7. Kligman AM. An overview of acne. J Invest Dermatol 1974; 62:268– 287. 8. Leeming JP, Holland KT, Cunliffe WJ. The microbiological ecology of pilosebaceous units from human skin. J Gen Microbiol 1984; 130:803– 807. 9. Hughes BR. The Structure and Function of the Pilosebaceous Duct in Health and Disease—with Special Reference to Acne Vulgaris.
He showed that corneocytes are arranged into three layers in the follicular impaction: a loosely attached outer layer; a densely packed middle layer; and a further loosely attached layer in the middle of the cast. Lipid droplets occur inside the cornified cells (38,175) and as a result the corneocytes become balloon-like in appearance. Abnormal lamellar inclusions of lipid have been described as a marker for abnormal keratinization (176). Scanning electron microscopy of comedonal contents revealed a complex system of numerous internal channels or “canaliculi” composed of concentric lamellae of corneocytes enclosing bacteria and sebum (177) (Fig.
Acne and its therapy by Guy F. Webster, Anthony V. Rawlings